Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062833 | 0.82 | HTT (0.52) | HTTFABP7 | |
| SCHEMBL6423668 | 0.81 | MAPK1 (0.34) | ALDH1A1 | |
| SCHEMBL10900754 | 0.80 | HTT (0.45) | HTTFABP7 | |
| SCHEMBL28682485 | 0.77 | HTT (0.42) | HTTALDH1A1 | |
| SCHEMBL6417698 | 0.76 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL6422346 | 0.76 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL4951808 | 0.75 | HTT (0.54) | HTTFABP7ALDH1A1 | |
| SCHEMBL7510764 | 0.75 | HTT (0.54) | HTTFABP7ALDH1A1 | |
| SCHEMBL2331335 | 0.75 | MAPT (0.48) | HTTALDH1A1 | |
| SCHEMBL8809039 | 0.74 | HTT (0.48) | HTTFABP7GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | claimed |