Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147781 | 1.00 | CES1 (0.40) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL147780 | 1.00 | CES1 (0.40) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL5885411 | 0.94 | APEX1 (0.37) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL1275312 | 0.94 | AKR1B1 (0.45) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL1275314 | 0.94 | AKR1B1 (0.45) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL487304 | 0.92 | GPR84 (0.47) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL423100 | 0.92 | GPR84 (0.47) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL423101 | 0.92 | GPR84 (0.47) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL154903 | 0.92 | GPR84 (0.47) | CES1APEX1CES2ALDH1A1AKR1B1 | |
| SCHEMBL142753 | 0.92 | GPR84 (0.47) | CES1APEX1CES2ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2273986-A2 | ENCAPSULATION OF BIOLOGICALLY ACTIVE AGENTS | Glaxo Group Limited (GB) | 2011-01-19 | — | — | EP | disclosed |
| EP-2271324-A2 | ENCAPSULATION OF BIOLOGICALLY ACTIVE AGENTS | Glaxo Group Limited (GB) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009135855-A2 | ENCAPSULATION OF BIOLOGICALLY ACTIVE AGENTS | GLAXO GROUP LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009135854-A2 | ENCAPSULATION OF BIOLOGICALLY ACTIVE AGENTS | GLAXO GROUP LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |