Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 10/20 | 0.69 |
| ▸ | RARB | P10826 | 10/20 | 0.69 |
| ▸ | RARA | P10276 | 8/20 | 0.69 |
| ▸ | RXRA | P19793 | 13/20 | 0.60 |
| ▸ | RXRB | P28702 | 5/20 | 0.59 |
| ▸ | RXRG | P48443 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050626 | 0.87 | RARB (0.69) | RARGRARBRARARXRARXRB | |
| SCHEMBL9049761 | 0.87 | RARB (0.69) | RARGRARBRARARXRARXRB | |
| SCHEMBL4192048 | 0.86 | RARB (0.67) | RARGRARBRARARXRARXRB | |
| SCHEMBL9048881 | 0.85 | RARB (0.66) | RARGRARBRARARXRARXRB | |
| SCHEMBL9049859 | 0.85 | RARB (0.66) | RARGRARBRARARXRARXRB | |
| SCHEMBL9117300 | 0.84 | RARB (0.54) | RARGRARBRARARXRARXRB | |
| SCHEMBL9050845 | 0.84 | RARB (0.64) | RARGRARBRARARXRARXRB | |
| SCHEMBL9050841 | 0.83 | RARB (0.60) | RARGRARBRARARXRARXRB | |
| SCHEMBL9051345 | 0.83 | RARB (0.63) | RARGRARBRARARXRARXRB | |
| SCHEMBL31266609 | 0.82 | RARB (1.00) | RARGRARBRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |
| WO-1995033745-A2 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | SRI INTERNATIONAL (US) | 1995-12-14 | — | — | WO | disclosed |