Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.68 |
| ▸ | HTR1B | P28222 | 3/20 | 0.68 |
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050530 | 0.88 | HTR1D (0.68) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9059222 | 0.83 | HTR1D (0.50) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9048907 | 0.82 | HTR1D (0.67) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9051166 | 0.81 | HTR1D (0.66) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9053172 | 0.80 | NPC1 (0.48) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9055858 | 0.79 | NPC1 (0.47) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9049449 | 0.79 | HTR1D (0.55) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL9301036 | 0.79 | HTR1D (0.82) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9053404 | 0.78 | HTR1D (0.54) | HTR1DHTR1BHTR2ARAB9ANPC1 | |
| SCHEMBL7803371 | 0.77 | HTR1D (1.00) | HTR1DHTR1BHTR2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724580-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011243-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |