Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054469 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL9701127 | 0.87 | KDM4E (0.74) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL10366509 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL10366511 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL7668621 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL7657864 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL7608332 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL7614102 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL13483613 | 0.84 | TOP1 (0.61) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL30626262 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001262-A1 | NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1996-01-18 | — | — | WO | claimed |
| WO-1996001262-A1 | NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1996-01-18 | — | — | WO | disclosed |