SCHEMBL9054488

SCHEMBL9054488

C=COC(=O)C(O)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
SRR Q9GZT4 2/20 0.42
ALPI P09923 1/20 0.42
PKM P14618 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
SLC7A5 Q01650 1/20 0.42
MDM2 Q00987 1/20 0.41
SLC15A1 P46059 1/20 0.41
CPA1 P15085 2/20 0.40
CPA3 P15088 2/20 0.40
FOLH1 Q04609 1/20 0.40
CPB1 P15086 1/20 0.40
CPB2 Q96IY4 1/20 0.40
TRPA1 O75762 1/20 0.39
MMP8 P22894 1/20 0.39
EPHX1 P07099 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7562088 0.81 CYP3A4 (0.50) CYP1A2SRRALPIPKMPTGS1
SCHEMBL27822152 0.81 CYP3A4 (0.50) CYP1A2SRRALPIPKMPTGS1
SCHEMBL7496164 0.81 CYP3A4 (0.50) CYP1A2SRRALPIPKMPTGS1
SCHEMBL6586336 0.81 ALPI (0.58) CYP1A2SRRALPIPKMPTGS1
SCHEMBL6593251 0.81 ALPI (0.58) CYP1A2SRRALPIPKMPTGS1
SCHEMBL28318428 0.81 CYP1A2 (0.43) CYP1A2SRRALPIPKMPTGS1
SCHEMBL8076531 0.81 HPGD (0.47) CYP1A2SRRMMP8NPC1RAB9A
SCHEMBL8076967 0.79 CYP1A2 (0.53) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL28214543 0.78 ATM (0.43) CYP1A2EPHX1
SCHEMBL979240 0.77 KMT2A (0.55) CYP1A2MMP8NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8020559-A None JP disclosed
JP-H0820559-A HYDROXYL GROUP-CONTAINING STYRENE DERIVATIVE AND MATERIAL FOR INTRAOCULAR LENS MADE OF THE HYDROXYL GROUP-CONTAINING STYRENE DERIVATIVE MENICON CO LTD 1996-01-23 JP disclosed