SCHEMBL28214543

SCHEMBL28214543

C=CN[C@@H](Cc1ccccc1)C(=O)OC=C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
TACR1 P25103 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
THRB P10828 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.41
CTSL P07711 1/20 0.41
MME P08473 1/20 0.40
EPHX1 P07099 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
PAM P19021 1/20 0.40
CYP1A2 P05177 1/20 0.40
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328715 0.84 TACR1 (0.60) ATMTACR1ALDH1A1CYP2C9CYP2C19
SCHEMBL284864 0.84 TACR1 (0.60) ATMTACR1ALDH1A1CYP2C9CYP2C19
SCHEMBL17633984 0.82 MME (0.53) MMECYP1A2
SCHEMBL8385283 0.82 MME (0.53) MMECYP1A2
SCHEMBL6716240 0.81 CTSL (0.53) ATMTACR1ALDH1A1CYP2C9CYP2C19
SCHEMBL6589100 0.81 CTSL (0.53) ATMTACR1ALDH1A1CYP2C9CYP2C19
Bromide SCHEMBL9748890 0.81 MME (0.51) MMECYP1A2
Bromide SCHEMBL9748887 0.81 MME (0.51) MMECYP1A2
SCHEMBL6588838 0.80 TACR1 (0.60) TACR1ALDH1A1CTSLCTSSCTSK
SCHEMBL9054488 0.78 CYP1A2 (0.44) EPHX1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003028-A Multi-unsaturated carboxylic acid's ester is synthesized by starting material of 1,3- dichloroisopropanols 王建华 2018-05-08 CN disclosed