SCHEMBL9054541

SCHEMBL9054541

CCS(=O)(=O)Nc1ccc([O])cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.67
LMNA P02545 3/20 0.67
HTT P42858 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.67
MAPT P10636 2/20 0.55
NR3C2 P08235 1/20 0.55
KIF11 P52732 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
AR P10275 1/20 0.50
PGR P06401 1/20 0.45
BRPF1 P55201 1/20 0.44
AURKB Q96GD4 2/20 0.43
PLK4 O00444 1/20 0.43
DAPK3 O43293 1/20 0.43
DYRK3 O43781 1/20 0.43
JAK2 O60674 1/20 0.43
ROCK2 O75116 1/20 0.43
MAP4K4 O95819 1/20 0.43
CDK1 P06493 1/20 0.43
RPS6KB1 P23443 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9156206 0.82 HPGD (0.60) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL7262812 0.82 HPGD (0.67) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL12309811 0.80 HPGD (0.77) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL6295481 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL6396662 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL9034826 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL7988528 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL19303636 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL10683547 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL981469 0.80 HPGD (0.64) HPGDLMNAHTTSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446863-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-06-05 EP disclosed
US-5476759-A Containing a coupler which releases a development inhibitor FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US disclosed
EP-0446863-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-18 EP disclosed
US-4874689-A POLYMER COUPLER; CHAIN TRANSFER AGENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-17 US disclosed
EP-0246616-A2 Silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1987-11-25 EP disclosed