Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293554 | 0.83 | HPGD (0.59) | HPGDLMNASMN1; SMN2CA1CA2 | |
| SCHEMBL2925053 | 0.81 | THRA (0.58) | HPGDLMNASMN1; SMN2HTTCA1 | |
| SCHEMBL18047835 | 0.81 | CA1 (0.55) | HPGDLMNASMN1; SMN2HTTCA1 | |
| SCHEMBL9054541 | 0.80 | HPGD (0.67) | HPGDLMNASMN1; SMN2HTTMAPT | |
| SCHEMBL7262812 | 0.80 | HPGD (0.67) | HPGDLMNASMN1; SMN2HTTCA1 | |
| SCHEMBL10886886 | 0.80 | LMNA (0.57) | HPGDLMNACA1CA2MAPT | |
| SCHEMBL8364601 | 0.80 | LMNA (0.57) | HPGDLMNACA1CA2MAPT | |
| SCHEMBL8361838 | 0.80 | LMNA (0.57) | HPGDLMNACA1CA2MAPT | |
| SCHEMBL7173254 | 0.80 | LMNA (0.57) | HPGDLMNACA1CA2MAPT | |
| SCHEMBL8756666 | 0.80 | LMNA (0.57) | HPGDLMNACA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017147526-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-31 | — | — | WO | disclosed |
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0446863-B1 | Silver halide color photographic material | FUJI PHOTO FILM CO LTD (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5476759-A | Containing a coupler which releases a development inhibitor | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| EP-0446863-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4874689-A | POLYMER COUPLER; CHAIN TRANSFER AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| EP-0246616-A2 | Silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |