Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | CCR10 | P46092 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330894 | 0.82 | DPP7 (0.44) | DPP7DPP4F2TLR9TLR8 | |
| SCHEMBL7330876 | 0.82 | DPP7 (0.44) | DPP7DPP4F2TLR9TLR8 | |
| SCHEMBL7331189 | 0.79 | F2 (0.56) | ITGB3ITGA2BDPP7DPP4F2 | |
| SCHEMBL9054873 | 0.78 | F2RL1 (0.39) | DPP7DPP4F2CCR10 | |
| SCHEMBL9054868 | 0.78 | F2RL1 (0.39) | DPP7DPP4F2CCR10 | |
| SCHEMBL9061843 | 0.77 | CCR10 (0.65) | F2CCR10 | |
| SCHEMBL2377257 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL20539968 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7331163 | 0.76 | F2 (0.61) | DPP7DPP4F2TLR9TLR8 | |
| SCHEMBL7331176 | 0.76 | F2 (0.61) | DPP7DPP4F2TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |