Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049480 | 0.77 | ALOX5 (0.67) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9049153 | 0.76 | ALOX5 (0.60) | ALOX5EPHX2HRH1ACACBACACA | |
| SCHEMBL6341962 | 0.76 | ALOX5 (0.68) | ALOX5EPHX2FLT3 | |
| SCHEMBL9047578 | 0.76 | ALOX5 (0.72) | ALOX5EPHX2HRH1ACACBACACA | |
| SCHEMBL9351477 | 0.76 | ALOX5 (0.65) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9047676 | 0.75 | ALOX5 (0.60) | ALOX5EPHX2HRH1ACACBACACA | |
| SCHEMBL9047411 | 0.75 | ALOX5 (1.00) | ALOX5EPHX2HRH1ACACBACACA | |
| SCHEMBL9049123 | 0.75 | ALOX5 (0.64) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL9048674 | 0.74 | ALOX5 (0.71) | ALOX5EPHX2ACACBACACA | |
| SCHEMBL26080884 | 0.74 | CYP2A6 (0.55) | ALOX5CYP2A6FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | claimed |