Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140911 | 0.84 | — | — | |
| SCHEMBL14733221 | 0.82 | ALDH1A1 (0.81) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL576751 | 0.76 | — | — | |
| SCHEMBL3835891 | 0.74 | ALDH1A1 (0.59) | ALDH1A1SOAT1MGAMGAASI | |
| Ethyne SCHEMBL167200 | 0.74 | ALDH1A1 (0.87) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL1332089 | 0.74 | — | — | |
| SCHEMBL1958756 | 0.74 | ALDH1A1 (1.00) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL3673 | 0.74 | — | — | |
| SCHEMBL7185101 | 0.73 | ALDH1A1 (0.65) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL5986896 | 0.73 | ALDH1A1 (0.65) | ALDH1A1SOAT1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690855-B1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LTD (GB) | 1996-12-18 | — | — | EP | claimed |