Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.70 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052596 | 0.91 | DRD2 (0.75) | DRD2DRD3ADRA1ADRD4SLC18A3 | |
| SCHEMBL9055902 | 0.87 | DRD2 (0.71) | DRD2DRD3ADRA1ADRD4SLC18A3 | |
| SCHEMBL9052631 | 0.84 | DRD2 (0.83) | DRD2DRD3ADRA1ADRD4SIGMAR1 | |
| SCHEMBL9051795 | 0.84 | DRD2 (0.71) | DRD2DRD3ADRA1ADRD4SLC18A3 | |
| SCHEMBL9051256 | 0.84 | DRD2 (0.71) | DRD2DRD3ADRA1ADRD4 | |
| SCHEMBL9053004 | 0.84 | DRD2 (0.67) | DRD2DRD3DRD4SLC18A3SIGMAR1 | |
| SCHEMBL9055748 | 0.83 | DRD2 (0.70) | DRD2DRD3ADRA1ADRD4SLC18A3 | |
| SCHEMBL9052699 | 0.82 | DRD2 (0.80) | DRD2DRD3ADRA1ADRD4SIGMAR1 | |
| SCHEMBL8986029 | 0.82 | DRD2 (1.00) | DRD2DRD3ADRA1ADRD4SIGMAR1 | |
| SCHEMBL9052139 | 0.81 | DRD2 (0.67) | DRD2DRD3ADRA1ADRD4SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |