Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | CCR10 | P46092 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055294 | 0.90 | ITGB3 (0.46) | ITGB3ITGAVITGA2BF2CCR10 | |
| SCHEMBL9056463 | 0.88 | F2 (0.44) | ITGB3ITGAVITGA2BF2PRSS1 | |
| SCHEMBL9055048 | 0.87 | F2 (0.53) | ITGB3ITGAVITGA2BF2CCR10 | |
| SCHEMBL9055118 | 0.85 | ITGB3 (0.42) | ITGB3ITGAVITGA2BF2CCR10 | |
| SCHEMBL9055624 | 0.85 | F2 (0.43) | ITGB3ITGAVITGA2BF2CCR10 | |
| SCHEMBL9055679 | 0.84 | F2 (0.43) | ITGB3ITGAVITGA2BF2CCR10 | |
| SCHEMBL9055403 | 0.83 | F2 (0.44) | ITGB3ITGAVITGA2BF2PRSS1 | |
| SCHEMBL9060435 | 0.83 | F2 (0.51) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055027 | 0.80 | F2 (0.44) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9056130 | 0.80 | F2 (0.41) | ITGB3ITGAVITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |