Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248313 | 0.83 | CA2 (0.39) | ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL576803 | 0.67 | MAPT (0.41) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL11099686 | 0.63 | MAPT (0.42) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL9671149 | 0.63 | MAPT (0.42) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL17860841 | 0.63 | MAPT (0.46) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL576708 | 0.63 | MAPT (0.46) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL11099684 | 0.63 | MAPT (0.42) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL8013804 | 0.63 | MAPT (0.50) | MAPTATMNPSR1LMNAALDH1A1 | |
| SCHEMBL24311920 | 0.62 | SMN1; SMN2 (0.43) | LMNAALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL980741 | 0.62 | CYP19A1 (0.40) | MAPTATMNPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8027132-A | — | — | None | — | — | JP | disclosed |
| JP-H0827132-A | PRODUCTION OF 5-OXAZOLONES | SHIRATORI SEIYAKU KK | 1996-01-30 | — | — | JP | disclosed |