SCHEMBL9055690

SCHEMBL9055690

CC(C)(CN)c1cnc(C(C)(C)CN)cn1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
SCN10A Q9Y5Y9 1/20 0.33
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22145964 0.84 HSP90AA1 (0.38) TAAR1
SCHEMBL1480763 0.78 NOS3 (0.43) TAAR1SCN10A
SCHEMBL18648250 0.76 HMGCR (0.32)
SCHEMBL9054350 0.75 TAAR1 (0.38) TAAR1
SCHEMBL24116762 0.70 TAAR1 (0.34) TAAR1
SCHEMBL1478334 0.70 SMN1; SMN2 (0.48) TAAR1CYP2D6
SCHEMBL30634160 0.70 SMN1; SMN2 (0.48) TAAR1CYP2D6
SCHEMBL12693700 0.70 NOS3 (0.34)
SCHEMBL15457955 0.70 HMGCR (0.33)
SCHEMBL14415969 0.69 CYP2C9 (0.46) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996000248-A1 WATER MISCIBLE NON-HYDROLYZABLE CROSS-LINKERS AND HIGH REFRACTIVE INDEX HYDROGELS PREPARED THEREWITH KABI PHARMACIA OPHTHALMICS, INC. (US) 1996-01-04 WO claimed