Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523983 | 0.89 | NPSR1 (0.50) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL5523980 | 0.89 | NPSR1 (0.50) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL9056102 | 0.85 | DHODH (0.43) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL9055868 | 0.83 | DHODH (0.49) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL8802032 | 0.81 | NPSR1 (0.42) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL9056464 | 0.79 | DHODH (0.45) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL10374437 | 0.78 | DHODH (0.55) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL9870075 | 0.78 | DHODH (0.55) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL9870077 | 0.78 | DHODH (0.55) | NPSR1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL10769548 | 0.78 | MEN1 (0.44) | NPSR1DHODHMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |