Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 4/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | YES1 | P07947 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416389 | 0.81 | HTR2C (0.59) | YES1KDRJAK3HTR6 | |
| SCHEMBL9056608 | 0.79 | CYP19A1 (0.55) | YES1KDRJAK3ALDH1A1KDM4E | |
| SCHEMBL8418190 | 0.78 | CYP19A1 (0.58) | YES1KDRJAK3ALDH1A1HTR6 | |
| SCHEMBL9055307 | 0.78 | YES1 (0.69) | YES1KDRJAK3HTR6 | |
| SCHEMBL8418207 | 0.78 | HTR2A (0.51) | SLC6A2ALDH1A1KDM4EHSD17B10HTR6 | |
| SCHEMBL27041029 | 0.75 | HTR2A (0.62) | DNM2CDC25AICMTCNR2ALDH1A1 | |
| SCHEMBL11361583 | 0.75 | CDC25A (0.56) | DNM2CDC25AICMTCNR2ALDH1A1 | |
| SCHEMBL11371748 | 0.75 | CDC25A (0.59) | DNM2CDC25AICMTCNR2ALDH1A1 | |
| SCHEMBL10967590 | 0.75 | CDC25A (0.66) | DNM2CDC25AICMTCNR2CNR1 | |
| SCHEMBL23269921 | 0.74 | CDC25A (0.65) | DNM2CDC25AICMTCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |