Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054532 | 0.86 | HTR2C (0.49) | HTR2AGPR84KDM4EMEN1KMT2A | |
| Maleic Acid SCHEMBL8415335 | 0.78 | MEN1 (0.48) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| Fumaric Acid SCHEMBL8415339 | 0.78 | MEN1 (0.48) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9056570 | 0.78 | HTR2C (0.51) | HTR2AGPR84KDM4EMEN1KMT2A | |
| SCHEMBL7004405 | 0.78 | HTR2A (0.73) | HTR2AGPR84KDM4EMEN1KMT2A | |
| SCHEMBL9055889 | 0.78 | DNM2 (0.47) | KDM4EHSD17B10TP53SLC6A2HTR6 | |
| SCHEMBL6351593 | 0.77 | HTR2A (0.59) | HTR2AGPR84KDM4EMEN1KMT2A | |
| SCHEMBL8418107 | 0.77 | CYP19A1 (0.56) | MEN1KMT2ARXFP1HTR6ALDH1A1 | |
| SCHEMBL14817117 | 0.77 | TP53 (0.55) | HTR2AGPR84KDM4EMEN1KMT2A | |
| SCHEMBL5096037 | 0.77 | GSK3B (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | claimed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | claimed |