SCHEMBL905614

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30716844	0.88	NPC1 (0.77)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL27775449	0.87	NPC1 (0.82)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL382207	0.86	TAS2R31 (0.79)	NPC1RAB9ATAS2R31TP53CYP3A4
	Dihydrooroxylin A SCHEMBL31682921	0.85	NPC1 (1.00)	NPC1RAB9ATAS2R31CYP3A4CYP19A1
	Dihydrooroxylin A SCHEMBL12067042	0.85	NPC1 (1.00)	NPC1RAB9ATAS2R31CYP3A4CYP19A1
	SCHEMBL31028356	0.84	CYP19A1 (0.87)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL7605704	0.84	TAS2R31 (0.65)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL28589889	0.83	TAS2R31 (0.64)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL30865912	0.83	TAS2R31 (0.64)	NPC1RAB9ATAS2R31TP53CYP3A4
	SCHEMBL14421486	0.83	TAS2R31 (0.57)	NPC1RAB9ATAS2R31TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.