Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R31 | P59538 | 1/20 | 0.79 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | XDH | P47989 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | KDM1A | O60341 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905614 | 0.86 | NPC1 (0.73) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL12067074 | 0.86 | TAS2R31 (0.83) | TAS2R31CYP19A1CYP3A4NPC1RAB9A | |
| SCHEMBL12067047 | 0.85 | TAS2R31 (0.81) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hamiltone B SCHEMBL29446946 | 0.85 | TAS2R31 (0.67) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hesperetin SCHEMBL765368 | 0.84 | CYP19A1 (1.00) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hesperetin SCHEMBL31689737 | 0.84 | CYP19A1 (1.00) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hesperetin SCHEMBL20929082 | 0.84 | CYP19A1 (1.00) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hesperetin SCHEMBL29484563 | 0.84 | CYP19A1 (1.00) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| Hesperetin SCHEMBL39833 | 0.84 | CYP19A1 (1.00) | TAS2R31CYP19A1TP53CYP3A4XDH | |
| SCHEMBL2124058 | 0.84 | CYP19A1 (0.68) | TAS2R31CYP19A1TP53CYP3A4XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360744-A1 | AGENT CONTAINING FLAVONOID DERIVATIVES FOR TREATING CANCER AND INFLAMMATION | FLAVOCURE BIOTECH INC. | 2017-12-21 | — | — | US | disclosed |
| EP-1503773-B9 | HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | COUNCIL SCIENT IND RES (IN) | 2012-01-25 | — | — | EP | disclosed |
| EP-1503773-B1 | HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | COUNCIL SCIENT IND RES (IN) | 2011-03-30 | — | — | EP | disclosed |
| EP-1509223-B1 | HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | disclosed |
| US-7259148-B2 | Hepatoprotective activity of 2′-p-hydroxybenzoylmussaenosidic acid | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-08-21 | — | — | US | disclosed |
| EP-1509223-A1 | HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN | Council Of Scientific And Industrial Research (IN) | 2005-03-02 | — | — | EP | disclosed |
| EP-1503773-A1 | HEPATOPROTECTIVE ACTIVITY OF 2 -P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | Council of Scientific and Industrial Research (IN) | 2005-02-09 | — | — | EP | disclosed |
| US-20040029816-A1 | Hepatoprotective activity of 10-O-P-hydroxybenzoyiaucubin | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-02-12 | — | — | US | disclosed |
| US-20040014684-A1 | Hepatoprotective activity of 2'-p-hydroxybenzoylmussaenosidic | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-01-22 | — | — | US | disclosed |
| WO-2003094946-A1 | HEPATOPROTECTIVE ACTIVITY OF 2'-P-HYDROXYBENZOYLMUSSAENOSIDIC ACID | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094911-A1 | HEPATOPROTECTIVE ACTIVITY OF 10-O-P-HYDROXYBENZOYIAUCUBIN | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360744-A1 | AGENT CONTAINING FLAVONOID DERIVATIVES FOR TREATING CANCER AND INFLAMMATION | TNF, NLRP3, F3 | TAS2R31 2271/4885CYP19A1 78/4885TP53 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.