Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609244 | 0.88 | NR2E1 (0.57) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL6612451 | 0.86 | NR2E1 (0.59) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL7407777 | 0.84 | NR2E1 (0.53) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7417242 | 0.83 | NR2E1 (0.52) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL8528531 | 0.81 | NR2E1 (0.63) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL31328285 | 0.81 | NISCH (0.46) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL7406266 | 0.77 | NR2E1 (0.55) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL30523188 | 0.77 | KDM4E (0.63) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL4728062 | 0.77 | KDM4E (0.63) | NR2E1HSD17B10MAPTHPGDKDM4E | |
| SCHEMBL30523189 | 0.77 | KDM4E (0.63) | NR2E1HSD17B10MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |