SCHEMBL9056416

SCHEMBL9056416

Nc1c(Cl)cc(S(=O)(=O)N[C@@H](CCCNc2ncc[nH]2)C(=O)NCC(=O)O)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.44
ITGAV P06756 19/20 0.44
ITGA2B P08514 18/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9055341 0.88 ITGB3 (0.40) ITGB3ITGAVITGA2B
SCHEMBL9056295 0.84 ITGB3 (0.43) ITGB3ITGAVITGA2B
SCHEMBL9055279 0.82 CCR10 (0.52) ITGB3ITGAVITGA2B
SCHEMBL9056014 0.82 ITGB3 (0.41) ITGB3ITGAVITGA2B
SCHEMBL9055147 0.81 ITGB3 (0.40) ITGB3ITGAVITGA2B
SCHEMBL9055268 0.81 ITGB3 (0.40) ITGB3ITGAVITGA2B
SCHEMBL9055818 0.81 CCR10 (0.46)
SCHEMBL9055586 0.81 ITGB3 (0.40) ITGB3ITGAVITGA2B
SCHEMBL9056040 0.80 ITGB3 (0.40) ITGB3ITGAVITGA2B
SCHEMBL9055886 0.80 ITGB3 (0.39) ITGB3ITGAVITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996002517-A1 SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS DR. KARL THOMAE GMBH (DE) 1996-02-01 WO disclosed