Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065832 | 0.85 | POLB (0.46) | CA12CA1CA2CA9LMNA | |
| SCHEMBL10791831 | 0.78 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11831412 | 0.78 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7971600 | 0.78 | MAOB (0.68) | CA12CA1CA2CA9MAPT | |
| SCHEMBL28994275 | 0.78 | CA12 (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL4874886 | 0.78 | CA12 (0.61) | CA12CA1CA2CA9LMNA | |
| SCHEMBL10602125 | 0.78 | MAOB (0.68) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9056197 | 0.78 | MAOB (0.65) | CA12CA1CA2CA9MAOB | |
| SCHEMBL28994493 | 0.77 | CA12 (0.53) | CA12CA1CA2CA9LMNA | |
| SCHEMBL20210894 | 0.76 | CA12 (0.46) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185319-B1 | FLUORO COUMARINS AS ANTILYMPHOEDEMA AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-06 | — | — | EP | claimed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | claimed |
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |
| EP-0185319-B1 | FLUORO COUMARINS AS ANTILYMPHOEDEMA AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-09-06 | — | — | EP | disclosed |
| US-4749798-A | ANTIINFLAMMATORY, ANTISWELLING | BOEHRINGER BIOCHEMIA ROBIN SPA (IT) | 1988-06-07 | — | — | US | disclosed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | disclosed |