Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859102 | 0.70 | MEN1 (0.33) | MEN1KMT2AGAA | |
| SCHEMBL11509637 | 0.70 | MEN1 (0.45) | MEN1KMT2AGAA | |
| SCHEMBL1406315 | 0.70 | MEN1 (0.55) | MEN1KMT2AGAA | |
| SCHEMBL4756149 | 0.70 | MEN1 (0.45) | MEN1KMT2ACASP1 | |
| SCHEMBL15134535 | 0.69 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL9629131 | 0.69 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL11561721 | 0.69 | MEN1 (0.44) | MEN1KMT2AGAA | |
| SCHEMBL9086970 | 0.69 | MEN1 (0.44) | MEN1KMT2AGAA | |
| SCHEMBL9190525 | 0.68 | MEN1 (0.44) | MEN1KMT2ACASP1GAA | |
| SCHEMBL25395739 | 0.67 | MEN1 (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | disclosed |