Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858117 | 0.79 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL15134535 | 0.78 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL24720928 | 0.77 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25395739 | 0.76 | MEN1 (0.42) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL15134540 | 0.76 | MEN1 (0.42) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL5676535 | 0.74 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4383428 | 0.74 | MEN1 (0.39) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| Water SCHEMBL28190510 | 0.73 | — | — | |
| SCHEMBL28307490 | 0.71 | TSHR (0.39) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL9056475 | 0.70 | MEN1 (0.50) | MEN1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |