Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054532 | 0.93 | HTR2C (0.49) | HTR2CHTR2AGPR84KEAP1NFE2L2 | |
| Maleic Acid SCHEMBL8415335 | 0.84 | MEN1 (0.48) | HTR2CCDK2MEN1KMT2AKDM4E | |
| Fumaric Acid SCHEMBL8415339 | 0.84 | MEN1 (0.48) | HTR2CCDK2MEN1KMT2AKDM4E | |
| SCHEMBL9055209 | 0.81 | HTR2C (0.79) | HTR2CHTR6KMT2ALMNA | |
| SCHEMBL8804198 | 0.80 | NOTUM (0.62) | MEN1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL14817117 | 0.79 | TP53 (0.55) | HTR2AGPR84KEAP1NFE2L2HTR6 | |
| SCHEMBL8418207 | 0.78 | HTR2A (0.51) | HTR2AGPR84KEAP1NFE2L2HTR6 | |
| SCHEMBL8415790 | 0.78 | HTR2C (0.67) | HTR2CHTR6MEN1KMT2ARXFP1 | |
| SCHEMBL8265671 | 0.77 | HTR2A (0.61) | HTR2AGPR84KEAP1NFE2L2HTR6 | |
| SCHEMBL8804773 | 0.77 | PTPN5 (0.64) | MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |