Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056112 | 0.87 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9057140 | 0.85 | PTPN2 (0.39) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9056310 | 0.84 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9056269 | 0.81 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9058024 | 0.78 | PDE3B (0.42) | LMNASMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL9056251 | 0.78 | PDE3B (0.42) | LMNASMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL9058030 | 0.78 | SCN9A (0.42) | — | |
| SCHEMBL9056198 | 0.78 | LMNA (0.37) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9056909 | 0.77 | SMN1; SMN2 (0.35) | LMNASMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9055880 | 0.77 | TDP1 (0.39) | LMNASMN1; SMN2KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |