SCHEMBL905677

SCHEMBL905677

O=S(=O)(O)c1ccccc1C(Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1)=C(Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RHOA P61586 1/20 0.47
TTR P02766 1/20 0.45
FABP4 P15090 1/20 0.45
CCNA2 P20248 1/20 0.45
CDK2 P24941 1/20 0.45
MAPK14 Q16539 1/20 0.45
CA12 O43570 5/20 0.44
CA1 P00915 5/20 0.44
CA2 P00918 5/20 0.44
CA9 Q16790 5/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
NR4A1 P22736 1/20 0.44
RECQL P46063 2/20 0.42
ALDH1A1 P00352 2/20 0.42
NSD2 O96028 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30398061 0.96 TTR (0.48) RHOATTRFABP4CCNA2CDK2
SCHEMBL3657587 0.96 TTR (0.48) RHOATTRFABP4CCNA2CDK2
SCHEMBL8626732 0.82 CA1 (0.42) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL30396962 0.81 CA1 (0.55) TTRFABP4CCNA2CDK2MAPK14
SCHEMBL5190368 0.81 CA12 (0.64) CA12CA1CA2CA9MAPT
SCHEMBL29437100 0.81 CA12 (0.64) CA12CA1CA2CA9MAPT
SCHEMBL10789781 0.79 RHOA (0.50) RHOACA12CA1CA2CA9
SCHEMBL6400413 0.79 TTR (0.40) RHOATTRFABP4CCNA2CDK2
SCHEMBL14759755 0.77 RHOA (0.43) RHOATTRFABP4CCNA2CDK2
SCHEMBL11119443 0.75 CA1 (0.45) CA12CA1CA2CA9APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261359-B1 Mannanases NOVOZYMES AS (DK) 2014-08-20 EP disclosed
EP-2284272-B1 Mannanases NOVOZYMES AS (DK) 2014-08-13 EP disclosed
EP-1572996-B1 DETERGENT COMPOSITION COMPRISING ENDO-GLUCANASE NOVOZYMES AS (DK) 2014-06-11 EP disclosed
EP-2311941-B1 Detergent composition comprising endo-glucanase NOVOZYMES AS (DK) 2014-03-19 EP disclosed
EP-2287318-B1 Mannanases NOVOZYMES AS (DK) 2014-01-22 EP disclosed
EP-0948610-B1 SUBTILASE VARIANTS AND COMPOSITIONS NOVOZYMES AS (DK) 2011-05-25 EP disclosed
EP-2311941-A1 Detergent composition comprising endo-glucanase Novozymes A/S (DK) 2011-04-20 EP disclosed
EP-2287318-A1 Mannanases Novozymes A/S (DK) 2011-02-23 EP disclosed
EP-2278001-A1 Protease variants and compositions Novozymes A/S (DK) 2011-01-26 EP disclosed
EP-1506292-B1 PECTATE LYASE VARIANTS NOVOZYMES AS (DK) 2011-01-05 EP disclosed
EP-0581752-A1 Built dye transfer inhibiting compositions THE PROCTER & GAMBLE COMPANY (US) 1994-02-02 EP disclosed
EP-0581753-A1 Dye transfer inhibiting compositions comprising polymeric dispersing agents THE PROCTER & GAMBLE COMPANY (US) 1994-02-02 EP disclosed
WO-1993021294-A1 USE OF MODIFIED POLYESTERS FOR THE WASHING OF COTTON-CONTAINING FABRICS THE PROCTER & GAMBLE COMPANY (US) 1993-10-28 WO disclosed
WO-1992018597-A1 COMPACT DETERGENT COMPOSITION CONTAINING POLYVINYLPYRROLIDONE THE PROCTER & GAMBLE COMPANY (US) 1992-10-29 WO disclosed
WO-1992018594-A1 PARTICULATE DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1992-10-29 WO disclosed
EP-0508034-A1 Compact detergent composition containing polyvinylpyrrolidone THE PROCTER & GAMBLE COMPANY (US) 1992-10-14 EP disclosed
WO-1992013798-A1 PEROXYACID BLEACH PRECURSOR COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1992-08-20 WO disclosed
WO-1992013053-A2 DETERGENT COMPOSITIONS WITH HIGH ACTIVITY CELLULASE AND SOFTENING CLAYS THE PROCTER & GAMBLE COMPANY (US) 1992-08-06 WO disclosed
WO-1992013057-A1 COMPACT DETERGENT COMPOSITIONS WITH HIGH ACTIVITY CELLULASE THE PROCTER & GAMBLE COMPANY (US) 1992-08-06 WO disclosed
EP-0342043-A2 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1989-11-15 EP disclosed