Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057060 | 1.00 | BAZ2A (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9055358 | 0.89 | HPGDS (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9055350 | 0.89 | HPGDS (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9056714 | 0.89 | BAZ2A (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9054087 | 0.89 | BAZ2A (0.39) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9054357 | 0.89 | FFAR4 (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9054364 | 0.89 | FFAR4 (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9054080 | 0.89 | BAZ2A (0.39) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9056725 | 0.89 | BAZ2A (0.36) | BAZ2AACHEHPGDSAOC3ITGB3 | |
| SCHEMBL9057498 | 0.88 | FFAR4 (0.34) | ACHEFFAR4DGAT1HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |