Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056577 | 0.86 | KMT2A (0.37) | POLBLMNAALDH1A1HTTPDE3B | |
| SCHEMBL9056198 | 0.84 | LMNA (0.37) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9056202 | 0.82 | SMN1; SMN2 (0.36) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9057380 | 0.80 | KMT2A (0.35) | LMNAMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL9057431 | 0.77 | LMNA (0.40) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9057433 | 0.77 | POLB (0.40) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9056310 | 0.74 | SMN1; SMN2 (0.36) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9056909 | 0.72 | SMN1; SMN2 (0.35) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9057475 | 0.70 | LMNA (0.42) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL9057832 | 0.70 | PDE3B (0.41) | POLBLMNAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |