Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 3/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057083 | 0.87 | DCUN1D1 (0.42) | TP53MAPTUBE2MDCUN1D1 | |
| SCHEMBL8807120 | 0.87 | GAA (0.48) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL8809258 | 0.84 | ROCK2 (0.57) | GAANPSR1THRBROCK2 | |
| SCHEMBL8812974 | 0.83 | CCR3 (0.43) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL8813280 | 0.82 | GAA (0.41) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL8807169 | 0.81 | ROCK2 (0.42) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL8809549 | 0.80 | GAA (0.44) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL9056291 | 0.80 | ROCK2 (0.43) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL8809317 | 0.80 | ROCK2 (0.43) | TP53MAPTGAANPSR1UBE2M | |
| SCHEMBL9059369 | 0.80 | GAA (0.49) | TP53MAPTGAANPSR1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |