Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969375 | 1.00 | POLB (1.00) | POLBTDP1MAPTTP53THRB | |
| SCHEMBL9057598 | 1.00 | POLB (1.00) | POLBTDP1MAPTTP53THRB | |
| SCHEMBL17465997 | 0.87 | POLB (0.77) | POLBTDP1MAPTTP53THRB | |
| SCHEMBL17465797 | 0.85 | POLB (0.73) | POLBTDP1MAPTTP53THRB | |
| SCHEMBL17466009 | 0.84 | POLB (0.73) | POLBTDP1MAPTTP53THRB | |
| SCHEMBL1176560 | 0.84 | POLB (0.72) | POLBTDP1MAPTTHRBALDH1A1 | |
| SCHEMBL1176559 | 0.84 | POLB (0.72) | POLBTDP1MAPTTHRBALDH1A1 | |
| SCHEMBL11781592 | 0.81 | POLB (0.68) | POLBTDP1MAPTALDH1A1KMT2A | |
| SCHEMBL22697045 | 0.80 | POLB (0.66) | POLBTDP1MAPTALDH1A1KMT2A | |
| SCHEMBL11097975 | 0.80 | POLB (0.66) | POLBTDP1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014292-A1 | PROCESS FOR THE PURIFICATION OF A NON-ENOLISABLE ESTER WITH A METALLIC REAGENT SELECTED FROM A METAL, A METAL OXIDE OR A METAL HYDRIDE | SALDANE LIMITED (IE) | 1996-05-17 | — | — | WO | claimed |
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |
| US-20170121344-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2017-05-04 | — | — | US | disclosed |
| US-9410035-B2 | Modified heterophasic polyolefin composition | MILLIKEN & COMPANY (US) | 2016-08-09 | — | — | US | disclosed |
| US-9410035-B2 | Modified heterophasic polyolefin composition | MILLIKEN & COMPANY (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160024289-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY | 2016-01-28 | — | — | US | disclosed |
| US-20160024289-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY | 2016-01-28 | — | — | US | disclosed |
| WO-2016014122-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |
| EP-2928470-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014089378-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | SIGA TECHNOLOGIES, INC. (US) | 2014-06-12 | — | — | WO | disclosed |
| WO-1996014292-A1 | PROCESS FOR THE PURIFICATION OF A NON-ENOLISABLE ESTER WITH A METALLIC REAGENT SELECTED FROM A METAL, A METAL OXIDE OR A METAL HYDRIDE | SALDANE LIMITED (IE) | 1996-05-17 | — | — | WO | disclosed |
| WO-1995032183-A1 | PROCESS FOR THE PREPARATION OF 2-CYANOACRYLOYL CHLORIDE AND USE OF THE COMPOUND SO PREPARED FOR THE PREPARATION OF ESTERS OF 2-CYANOACRYLIC ACID | SALDANE LIMITED (IE) | 1995-11-30 | — | — | WO | disclosed |
| US-4749772-A | POLYESTER REACTED WITH CYANO(METH)ACRYLATE SUBSTITUTED WITH FURANYL OR THIENYL | EASTMAN KODAK COMPANY (US) | 1988-06-07 | — | — | US | disclosed |
| US-4049662-A | HYPOTENSIVE AGENTS, VASODILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4016277-A | ANTIHYPERTENSIVE AGENTS AND CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4004014-A | VASODILATION, HYPOTENSIVE, ANTIARRHYTHMIA, SPASMOLYTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | disclosed |
| US-3988458-A | HYPOTENSIVE, CORONARY DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3959474-A | 2,6-Diamino-1,4-dihydropyridine-3,5-dicarboxylic acid esters used as coronary vessel dilators and anti-hypertensive agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3957998-A | ADMINISTERING | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3950336-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121344-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | TTPA, TPMT, SLC19A2 | POLB 4278/4885TDP1 484/4885MAPT 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.