⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249254 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL21879614 | 0.97 | — | — | |
| SCHEMBL29249245 | 0.97 | — | — | |
| Formic Acid SCHEMBL30381140 | 0.84 | CYP1A2 (0.36) | — | |
| Phosphoric Acid SCHEMBL30061404 | 0.84 | GRM4 (0.44) | — | |
| SCHEMBL10580520 | 0.79 | — | — | |
| SCHEMBL964999 | 0.79 | AAK1 (0.32) | — | |
| SCHEMBL19249163 | 0.78 | CYP1A2 (0.31) | — | |
| SCHEMBL903053 | 0.76 | — | — | |
| SCHEMBL24355379 | 0.76 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4281461-B1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2026-01-21 | — | — | EP | claimed |
| US-20240116916-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-HYDROXY-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2024-04-11 | — | — | US | claimed |
| US-20240101575-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2024-03-28 | — | — | US | claimed |
| EP-4281462-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2023-11-29 | — | — | EP | claimed |
| EP-4281448-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-HYDROXY-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2023-11-29 | — | — | EP | claimed |
| EP-4281461-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2023-11-29 | — | — | EP | claimed |
| EP-4138829-A1 | AAK1 INHIBITORS FOR USE IN TREATING VIRAL INFECTIONS | Lexicon Pharmaceuticals, Inc. (US) | 2023-03-01 | — | — | EP | claimed |
| EP-4032893-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2022-07-27 | — | — | EP | claimed |
| EP-4032894-A1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2022-07-27 | — | — | EP | claimed |
| EP-0672739-B1 | THERMOREVERSIBLE THICKENER | SANYO CHEMICAL IND LTD (JP) | 2001-01-03 | — | — | EP | claimed |
| EP-0623578-B1 | Process for the preparation of dichloroacetylchloride | HOECHST AG (DE) | 1997-08-13 | — | — | EP | claimed |
| EP-0623578-A1 | Process for the preparation of dichloroacetylchloride | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-09 | — | — | EP | claimed |
| US-4495229-A | SECONDARY AMINE-BLOCKED POLYISOCYANATE-DEBLOCKING AT LOW TEMPERATURE | CHEMISCHE WERKE HULS A.G. (DE) | 1985-01-22 | — | — | US | claimed |
| US-12559507-B2 | Method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-ajpyrimidin-4-ium-5-olate | BASF SE (DE) | 2026-02-24 | — | — | US | disclosed |
| EP-4281461-B1 | METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE | BASF SE (DE) | 2026-01-21 | — | — | EP | disclosed |
| CN-119899179-A | AAK1 inhibitor and application thereof | 安润医药科技（苏州）有限公司 | 2025-04-29 | — | — | CN | disclosed |
| EP-0491525-A1 | Benzamide and sulfonamide hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0260644-B1 | PROCESS FOR THE MANUFACTURE OF ALPHA-PYRROLIDONES AND THEIR IMINES | BASF Aktiengesellschaft (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0260644-A1 | Process for the manufacture of alpha-pyrrolidones and their imines | BASF Aktiengesellschaft (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0119428-A2 | Biscarboxamides for treating diseases, and process for their preparation | BAYER AG (DE) | 1984-09-26 | — | — | EP | disclosed |