Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810832 | 0.75 | G6PC1 (0.46) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL8818077 | 0.73 | G6PC1 (0.44) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL20871938 | 0.72 | KDM4E (0.62) | HRH3HRH4KMT2AOPRM1SLC18A3 | |
| SCHEMBL12730900 | 0.71 | KMT2A (0.58) | MC4RMEN1RAB9AKMT2ACHRM2 | |
| SCHEMBL24323034 | 0.71 | G6PC1 (0.51) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL7603670 | 0.71 | HRH3 (0.73) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL8172289 | 0.71 | G6PC1 (0.51) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL8442356 | 0.70 | KDM4E (0.68) | HRH3HRH4KMT2AOPRM1 | |
| SCHEMBL515999 | 0.70 | G6PC1 (0.54) | HRH3G6PC1AGERUSP2HPGD | |
| SCHEMBL7885548 | 0.70 | G6PC1 (0.54) | HRH3G6PC1AGERUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |