Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040323 | 1.00 | L3MBTL1 (0.72) | L3MBTL1TDP1NPC1LMNAHTT | |
| SCHEMBL597834 | 0.88 | L3MBTL1 (0.69) | L3MBTL1NPC1LMNAHTTKMT2A | |
| SCHEMBL5725941 | 0.87 | L3MBTL1 (0.68) | L3MBTL1TDP1NPC1LMNAHTT | |
| SCHEMBL8853339 | 0.86 | NPC1 (0.65) | L3MBTL1TDP1NPC1HTTKMT2A | |
| SCHEMBL24603113 | 0.84 | L3MBTL1 (0.65) | L3MBTL1TDP1NPC1LMNAHTT | |
| SCHEMBL8636638 | 0.84 | NPC1 (0.61) | L3MBTL1NPC1LMNAHTTKMT2A | |
| SCHEMBL3922719 | 0.84 | HSD17B10 (0.69) | L3MBTL1NPC1LMNAHTTKMT2A | |
| SCHEMBL24603004 | 0.83 | L3MBTL1 (0.60) | L3MBTL1TDP1NPC1LMNAHTT | |
| SCHEMBL29270111 | 0.83 | KMT2A (0.61) | L3MBTL1NPC1LMNAHTTKMT2A | |
| SCHEMBL27917764 | 0.83 | KMT2A (0.56) | L3MBTL1NPC1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012489-A1 | BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |