Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703304 | 0.97 | MAPT (0.55) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8703773 | 0.92 | RBP4 (0.51) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8703751 | 0.90 | MAPT (0.48) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8703929 | 0.90 | RBP4 (0.47) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL6960671 | 0.90 | KMT2A (0.47) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8703466 | 0.89 | MAPT (0.48) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8699319 | 0.88 | RBP4 (0.45) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8704891 | 0.88 | MAPT (0.53) | MAPTLMNAALDH1A1TP53CA12 | |
| SCHEMBL8704931 | 0.88 | RBP4 (0.57) | MAPTLMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8702942 | 0.87 | MAPT (0.53) | MAPTLMNAALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |