Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 3/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057960 | 0.87 | SMN1; SMN2 (0.36) | PYGMCDASLC28A1SLC28A2SLC29A1 | |
| SCHEMBL21357702 | 0.85 | CDA (0.40) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL65271 | 0.85 | CDA (0.40) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9213688 | 0.84 | SLC29A1 (0.44) | ADORA2AADORA2BSLC28A1SLC28A2SLC29A1 | |
| SCHEMBL9368753 | 0.82 | TK2 (0.40) | CDALMNASMN1; SMN2 | |
| SCHEMBL8720503 | 0.82 | CDA (0.38) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9572140 | 0.82 | TK2 (0.41) | ADORA2AADORA2BCDA | |
| SCHEMBL9572128 | 0.82 | TK2 (0.41) | ADORA2AADORA2BCDA | |
| SCHEMBL9368671 | 0.82 | TK2 (0.41) | ADORA2AADORA2BCDA | |
| SCHEMBL9572133 | 0.82 | TK2 (0.41) | ADORA2AADORA2BCDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | disclosed |
| EP-0602454-A1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |