Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | CDA | P32320 | 3/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | THPO | P40225 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057982 | 0.87 | ADORA2A (0.37) | SMN1; SMN2PYGMCDASLC28A1SLC28A2 | |
| SCHEMBL21357702 | 0.84 | CDA (0.40) | SMN1; SMN2ALDH1A1HTTBLMTSHR | |
| SCHEMBL65271 | 0.84 | CDA (0.40) | SMN1; SMN2ALDH1A1HTTBLMTSHR | |
| SCHEMBL9213688 | 0.83 | SLC29A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3LMNA | |
| SCHEMBL8720503 | 0.81 | CDA (0.38) | SMN1; SMN2ALDH1A1HTTBLMTSHR | |
| SCHEMBL29845228 | 0.78 | CDA (0.41) | SMN1; SMN2ALDH1A1HTTBLMPYGM | |
| SCHEMBL10903345 | 0.78 | CDA (0.42) | SMN1; SMN2ALDH1A1HTTBLMPYGM | |
| SCHEMBL9368753 | 0.78 | TK2 (0.40) | SMN1; SMN2ALDH1A1CDALMNAPOLB | |
| SCHEMBL3630509 | 0.78 | LMNA (0.45) | SMN1; SMN2ALDH1A1HTTBLMPYGM | |
| SCHEMBL6906558 | 0.78 | LMNA (0.45) | SMN1; SMN2ALDH1A1HTTBLMPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602454-B1 | N-Oxycarbonyl substituted 5'-deoxy-5-fluorocytidines | HOFFMANN LA ROCHE (CH) | 1996-04-24 | — | — | EP | disclosed |