Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056810 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL10594661 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL9057375 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL8750117 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL9056035 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL9057349 | 1.00 | PTPN11 (0.46) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL10594668 | 0.95 | PTPN11 (0.48) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL10588443 | 0.95 | PTPN11 (0.48) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL9306701 | 0.94 | PTPN11 (0.41) | PTPN11RARBHDAC3HDAC4HDAC1 | |
| SCHEMBL10439304 | 0.89 | THRA (0.43) | PTPN11RARBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327349-B1 | Liquid crystal compounds | SHOWA SHELL SEKIYU (JP) | 1996-04-10 | — | — | EP | disclosed |