Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057893 | 0.86 | CA2 (0.50) | CA2CA4HRH3 | |
| SCHEMBL9057643 | 0.85 | CA2 (0.47) | CA2CA4 | |
| SCHEMBL9058838 | 0.84 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL9058019 | 0.82 | CA2 (0.47) | CA2CA4 | |
| SCHEMBL9058281 | 0.80 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL9057348 | 0.80 | CA2 (0.49) | CA2CA4 | |
| SCHEMBL9058819 | 0.79 | CA2 (0.35) | CA2CA4 | |
| SCHEMBL9115575 | 0.79 | CA2 (0.46) | CA2CA4MAPT | |
| SCHEMBL9058328 | 0.79 | CA2 (0.50) | CA2CA4 | |
| SCHEMBL9058087 | 0.79 | CA2 (0.46) | CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | claimed |
| WO-1996022099-A1 | OPHTHALMIC COMPOSITIONS FOR TREATING GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |