Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238944 | 0.92 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10719972 | 0.85 | HTT (0.78) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7232379 | 0.82 | HTT (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7238728 | 0.80 | HTT (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3455691 | 0.79 | HTT (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17730097 | 0.79 | HTT (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL95918 | 0.79 | HTT (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29941294 | 0.79 | HTT (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5165728 | 0.79 | GAA (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7925071 | 0.78 | CA12 (0.55) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |