Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 8/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058809 | 0.87 | MKNK1 (0.39) | MKNK1ACACBCYP1A2CYP2C9MAPK1 | |
| SCHEMBL9058715 | 0.87 | MKNK1 (0.39) | MKNK1ACACBCYP1A2CYP2C9MAPK1 | |
| SCHEMBL9058799 | 0.84 | MKNK1 (0.38) | MKNK1ACACBCYP1A2CYP2C9MAPK1 | |
| SCHEMBL22834815 | 0.76 | CYP1A2 (0.47) | CYP1A2CYP2C9FYN | |
| SCHEMBL9058720 | 0.76 | MKNK1 (0.35) | MKNK1CYP1A2CYP2C9LMNAMAPK1 | |
| SCHEMBL9058563 | 0.76 | MKNK1 (0.35) | MKNK1CYP1A2CYP2C9LMNAMAPK1 | |
| SCHEMBL11734584 | 0.74 | CYP1A2 (0.43) | MKNK1CYP1A2CYP2C9LMNAMAPK1 | |
| SCHEMBL9058560 | 0.74 | MKNK1 (0.34) | MKNK1CYP1A2CYP2C9MAPK1ATM | |
| SCHEMBL9058711 | 0.74 | MKNK1 (0.34) | MKNK1CYP1A2CYP2C9MAPK1ATM | |
| SCHEMBL7998348 | 0.73 | CYP1A2 (0.45) | CYP1A2CYP2C9LMNAMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016656-A1 | CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-06 | — | — | WO | disclosed |