Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058711 | 1.00 | MKNK1 (0.34) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058563 | 0.89 | MKNK1 (0.35) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058720 | 0.89 | MKNK1 (0.35) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9059217 | 0.88 | ALDH1A1 (0.35) | MKNK1CYP1A2CYP2C9MAPK1ATM | |
| SCHEMBL9058809 | 0.80 | MKNK1 (0.39) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058715 | 0.80 | MKNK1 (0.39) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058561 | 0.79 | MKNK1 (0.38) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058316 | 0.77 | CYP1A2 (0.32) | CYP1A2CYP2C9MAPK1ATM | |
| SCHEMBL9058799 | 0.77 | MKNK1 (0.38) | MKNK1DYRK3CCNA2CDK2DYRK1A | |
| SCHEMBL9058315 | 0.74 | MKNK1 (0.41) | MKNK1CYP1A2CYP2C9MAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016656-A1 | CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-06 | — | — | WO | claimed |
| WO-1996016656-A1 | CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-06 | — | — | WO | disclosed |