SCHEMBL9058441

SCHEMBL9058441

CCCCC(CC)CNc1cccc(C(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.49
NR1H4 Q96RI1 6/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 2/20 0.45
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058984 0.83 TSHR (0.46) ALDH1A1KDM4ETSHRL3MBTL1GLA
SCHEMBL3248985 0.80 ALDH1A1 (0.56) ALDH1A1KDM4ETSHRL3MBTL1GLA
SCHEMBL22176874 0.80 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRL3MBTL1GLA
SCHEMBL9114365 0.79 MAPT (0.50) ALDH1A1KDM4ETSHRL3MBTL1GLA
Benzoic Acid SCHEMBL8603617 0.79 ALDH1A1 (0.65) ALDH1A1KDM4ETSHRL3MBTL1GLA
SCHEMBL6325442 0.79 AKR1C3 (0.58) AKR1C3NR1H4SMN1; SMN2
Hydrochloric Acid SCHEMBL11405504 0.78 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRL3MBTL1GLA
SCHEMBL12802131 0.78 ALDH1A1 (0.56) AKR1C3NR1H4ALDH1A1KDM4EL3MBTL1
SCHEMBL9231035 0.77 NR1H4 (0.56) AKR1C3NR1H4ALDH1A1
SCHEMBL18425464 0.77 SMN1; SMN2 (0.43) ALDH1A1KDM4ETSHRL3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996017589-A1 METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS KAO CORPORATION (JP) 1996-06-13 WO disclosed