Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.64 |
| ▸ | HTR1D | P28221 | 10/20 | 0.64 |
| ▸ | HTR1B | P28222 | 10/20 | 0.64 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312894 | 0.85 | HTR1A (0.75) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL6313105 | 0.84 | HTR1A (0.70) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL9058832 | 0.82 | HTR1A (0.65) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL6313934 | 0.81 | HTR1A (0.66) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL27371183 | 0.80 | HTR1A (0.65) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL6314963 | 0.80 | HTR1A (0.67) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL6312484 | 0.79 | HTR1A (0.69) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL27393719 | 0.78 | HTR1A (0.65) | HTR1AHTR1DHTR1BSLC6A9KCNH2 | |
| SCHEMBL8902021 | 0.78 | HTR1A (0.52) | HTR1AMET | |
| SCHEMBL7809209 | 0.76 | HTR1A (0.64) | HTR1AHTR1DHTR1BSLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012713-A1 | NOVEL NAPHTHYLPIPERAZINE-DERIVED AROMATIC ETHERS FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012713-A1 | NOVEL NAPHTHYLPIPERAZINE-DERIVED AROMATIC ETHERS FOR USE AS DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |