Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.49 |
| ▸ | FNTB | P49356 | 14/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392096 | 0.90 | FNTA (0.52) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8392306 | 0.90 | FNTA (0.51) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8392299 | 0.90 | FNTA (0.51) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL9052592 | 0.82 | FNTA (0.47) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8388772 | 0.80 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8388776 | 0.76 | CYP11B1 (0.52) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL9051587 | 0.74 | FNTA (0.47) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8389012 | 0.74 | FNTA (0.49) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL9052376 | 0.74 | FNTA (0.47) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL8389739 | 0.74 | FNTA (0.47) | FNTAFNTBCYP11B1CYP11B2PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | claimed |
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | disclosed |