Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.52 |
| ▸ | FNTA | P49354 | 12/20 | 0.49 |
| ▸ | FNTB | P49356 | 12/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389708 | 0.92 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8392096 | 0.88 | FNTA (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9052035 | 0.86 | FNTA (0.48) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8388840 | 0.86 | FNTA (0.48) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8392037 | 0.85 | CTSB (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9051478 | 0.84 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8390690 | 0.84 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8388772 | 0.82 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8389606 | 0.78 | CTSB (0.43) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL9058692 | 0.76 | FNTA (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972984-A | LOW MOLECULAR WEIGHT PEPTIDYL COMPOUNDS THAT DO NOT HAVE A THIOL MOIETY. | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996039137-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-12-12 | — | — | WO | disclosed |