Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 16/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8863368 | 0.99 | CHRM1 (0.61) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL1760904 | 0.92 | OPRM1 (0.57) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL8672729 | 0.88 | CHRM1 (0.63) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL5482356 | 0.85 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL8349502 | 0.84 | OPRM1 (0.61) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL3414573 | 0.84 | CHRM1 (0.53) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL14365466 | 0.83 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13823764 | 0.83 | OPRM1 (0.61) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Trifluoroacetic Acid SCHEMBL15574954 | 0.82 | OPRM1 (0.48) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL3710702 | 0.82 | CHRM1 (0.78) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | disclosed |