Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055192 | 0.81 | CTNNB1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2CTNNB1 | |
| SCHEMBL16313719 | 0.81 | MAPT (0.44) | MAPTKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8672674 | 0.81 | CYP19A1 (0.59) | CYP19A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8670350 | 0.81 | CYP19A1 (0.59) | CYP19A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8519711 | 0.81 | CYP19A1 (0.59) | CYP19A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28715216 | 0.81 | EP300 (0.53) | CYP19A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6746832 | 0.80 | CYP19A1 (0.54) | CYP19A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL31211720 | 0.79 | CYP19A1 (0.66) | CYP19A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4446464 | 0.79 | GPR52 (0.48) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3803604 | 0.78 | KDM4E (0.48) | CYP19A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8262868-A | — | — | None | — | — | JP | disclosed |
| EP-4727948-A1 | ANTIMALARIAL AGENTS | Merck Sharp & Dohme LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024254795-A1 | ANTIMALARIA AGENTS | MERCK SHARP & DOHME LLC (US) | 2024-12-19 | — | — | WO | disclosed |
| WO-2024258769-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2024-12-19 | — | — | WO | disclosed |
| JP-H08262868-A | DEVELOPING ROLL AND DEVELOPING DEVICE | TOKAI RUBBER IND LTD | 1996-10-11 | — | — | JP | disclosed |